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factor VIII

American  
factor VIII British  

noun

  1. a protein that participates in the clotting of blood. It is extracted from donated serum and used in the treatment of the commonest type of haemophilia, in which it is absent

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of factor VIII

First recorded in 1960–65

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Only 15% of people with haemophilia have haemophilia B. Most have haemophilia A—a genetic disorder caused by a deficiency in a different blood-clotting protein called factor VIII, which is encoded by a different gene.

From Scientific American Dec. 9, 2022

They cannot carry a large gene, and the gene for factor VIII, needed to treat hemophilia A, is enormous.

From New York Times Aug. 13, 2018

Like 2,000 other people in the UK, his body could not make clotting factor VIII.

From BBC Dec. 13, 2017

For factor VIII, Fc fusion extends the half-life from a maximum of about 12 hours to about 18 hours.

From Nature Nov. 25, 2014

The two main forms of the disease are hemophilia A, caused by a lack of clotting factor VIII, and hemophilia B, caused by a lack of clotting factor IX.

From Reuters Dec. 11, 2011

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