fibrosis

American  

[fahy-broh-sis] / faɪˈbroʊ sɪs /

noun

Pathology.

1. the development in an organ of excess fibrous connective tissue.

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fibrosis British  

/ faɪˈbrəʊsɪs, faɪˈbrɒtɪk /

noun

1. the formation of an abnormal amount of fibrous tissue in an organ or part as the result of inflammation, irritation, or healing

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Other Word Forms

• fibrotic adjective

Etymology

Origin of fibrosis

First recorded in 1870–75; fibr- + -osis

Example Sentences

The company reported that the Tyvaso trial, TETON-1, showed a magnitude of improvement in treating idiopathic pulmonary fibrosis, or IPF, when compared with the first Phase 3 trial.

From Barron's • Mar. 30, 2026

Born with cystic fibrosis, a genetic disorder that causes mucus to become thick and sticky, she has just 9% lung function.

From BBC • Mar. 24, 2026

The crown princess, 52, who suffers from the lung disease pulmonary fibrosis, made clear that everything depended on her state of health.

From BBC • Mar. 20, 2026

Further analysis showed reduced activity in genes linked to fibrosis, including those involved in collagen production, in the livers of treated mice.

From Science Daily • Mar. 18, 2026

A folded dollar bill holding down the switch, stopping the alarm from blaring and letting everyone in the hospital know some crazy guy with cystic fibrosis and self-destructive tendencies is hanging out on the roof.

From "Five Feet Apart" by Rachael Lippincott