first-line
Americanadjective
-
available for immediate service, especially combat service.
first-line troops.
-
of prime importance or quality.
adjective
Etymology
Origin of first-line
First recorded in 1895–1900
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Early-stage data for GSK’s drug candidate IDRx-42 presented at the American Society of Clinical Oncology’s annual meeting showed potential as a first-line treatment for gastrointestinal cancer, Jefferies says.
From The Wall Street Journal ● Jun. 2, 2026
Researchers noted that these reductions are similar to results seen with some first-line blood pressure medications.
From Science Daily ● May 10, 2026
Each time, the first-line representative said no, suggesting something like, “If you can’t afford to pay it now, set up a payment plan or apply for financial assistance.”
From Slate ● Apr. 25, 2026
Nektar stock jumped 26% after positive trial results, with analysts raising price targets and expecting first-line treatment potential.
From Barron's ● Apr. 20, 2026
Their prison hospital X-ray machines were in a decrepit state, and there was a chronic shortage of even first-line antibiotics.
From "Mountains Beyond Mountains" by Tracy Kidder and Michael French
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.