fluxe is not in our dictionary (yet). Here's what it could mean:

Example Sentences

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Tobias Atkins the gunners boy died of the fluxe, who was buried the 6. day 2. miles to the Southward of the Castle of Derbent, where the Armenian Christians do vsually bury their dead.

From The Principal Navigations, Voyages, Traffiques and Discoveries of the English Nation — Volume 04 by Hakluyt, Richard

This word was originally spelt with e, axe; and so also was nearly every corresponding word of one syllable: as, flaxe, taxe, waxe, sixe, mixe, pixe, oxe, fluxe, etc.

From Webster's Unabridged Dictionary (2nd 100 Pages) by Webster, Noah