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focal segmental glomerulosclerosis

n.
  1. Segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix, seen sometimes in nephrotic syndrome or mesangial proliferative glomerulonephritis.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.