G-protein

American  

noun

G-proteins plural

1. Biochemistry. any of a class of proteins in the membrane of a cell that mediate between hormone receptors on the cell surface and enzymes whose response allows the cell to regulate its metabolism.

---

G-protein Scientific  

/ jē′prō′tēn′ /

1. Any of a class of cell membrane proteins that function as intermediaries between hormone receptors and enzymes that enable the cell to regulate its metabolism in response to hormonal changes.

---

Other Word Forms

Noun Inflected Forms

• G-proteins
  plural

Example Sentences

See Examples For:

G-protein G-proteins

"G-protein coupled receptors, normally, can be activated by specific small molecules that bind in a pocket in the receptor," explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab and co-lead author of the paper.

From Science Daily ● Dec. 4, 2024

This region is critical to form a signaling complex, which helps to transfer the signal from the taste receptor to the G-protein to the taste receptor cells.

From Science Daily ● Apr. 10, 2024

"We also have the ability to affect specific G-protein subtypes, like G-protein alpha or G-protein beta, rather than other G-protein pathways that we don't want to cause any other side effects."

From Science Daily ● Apr. 10, 2024

One or both of these G-protein fragments may be able to activate other proteins as a result.

From Textbooks ● Jun. 9, 2022

When a hormone is not bound to the receptor, the G-protein is inactive and is bound to guanosine diphosphate, or GDP.

From Textbooks ● Jun. 9, 2022

"One class of such promising agents is the PCAIs that were designed to target oncogenic G-proteins in a manner that is different from the KRASG12C-targeting drugs."

From Science Daily ● Jun. 29, 2026

They discovered that G-proteins impact the function of specific voltage sensors, but not others, making them more "reluctant" to sense electrical signals.

From Science Daily ● Nov. 18, 2024

Their analysis confirmed that GPR156 activation hinges on its interaction with abundant lipids in the cell membrane, triggering structural shifts upon engagement with G-proteins in the cytoplasm.

From Science Daily ● Apr. 15, 2024

The binding of a hormone at a single receptor causes the activation of many G-proteins, which activates adenylyl cyclase.

From Textbooks ● Jun. 9, 2022

When a hormone binds to its membrane receptor, a G- protein that is associated with the receptor is activated; G-proteins are proteins separate from receptors that are found in the cell membrane.

From Textbooks ● Jun. 9, 2022