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galantamine

/ ɡəˈlæntəˌmiːn /

noun

  1. a drug that, by blocking the action of the enzyme acetylcholinesterase in the cortex of the brain, has been used to slow down the cognitive decline that characterizes Alzheimer's disease

“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Believed to have been brought to Britain by the Romans, daffodils are a source of galantamine, a treatment for Alzheimer's disease.

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Galantamine is a common medication used by people with Alzheimer's disease and other forms of dementia around the world to treat their symptoms.

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In a paper in Nature Communications, researchers outline a process using genetically modified bacteria to create a chemical precursor of galantamine as a byproduct of the microbe's normal cellular metabolism.

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The research team genetically modified E. coli to produce 4-O'Methyl-norbelladine, a chemical building block of galantamine.

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The main drugs prescribed to people with early stage memory loss — donepezil, rivastigmine and galantamine — promote cholinergic signalling by inhibiting acetylcholine degradation to maintain its levels in the extracellular space119, which is thought to promote neuronal activity and improve cholinergic tone.

Read more on Nature

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