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gastrointestinal

American

[gas-troh-in-tes-tuh-nl] / ˌgæs troʊ ɪnˈtɛs tə nl /

adjective

Anatomy.

of, relating to, or affecting the stomach and intestines.

gastrointestinal British

/ ˌɡæstrəʊɪnˈtɛstɪnəl /

adjective

of or relating to the stomach and intestinal tract

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of gastrointestinal

First recorded in 1825–35; gastro- + intestinal

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Shigella and salmonella are gastrointestinal infections which can cause diarrhoea, stomach cramps and fever.

From BBC • Apr. 7, 2026

He entered the program with a history of gastrointestinal issues and abdominal surgeries.

From Los Angeles Times • Apr. 5, 2026

Between 40 and 70 percent of patients on these drugs report gastrointestinal adverse effects, like acid reflux, chronic diarrhea, and/or constipation.

From Slate • Mar. 22, 2026

Beyond mammary cancer, the researchers identified similarities to human cancer mutations in tumors affecting the blood, bone, lungs, skin, gastrointestinal system, and central nervous system.

From Science Daily • Mar. 18, 2026

For centuries many of the inhabitants of this region suffered from what came to be known as “the Reichenstein disease” — chronic arsenicism with accompanying disorders of the liver, skin, and gastrointestinal and nervous systems.

From "Silent Spring" by Rachel Carson

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023