- a syphilitic brain disorder characterized by chronic inflammation and degeneration of cerebral tissue resulting in mental and physical deterioration.
Origin of general paralysis
First recorded in 1890–95
Also called general paresis.
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- A brain disease occurring as a late consequence of syphilis, characterized by dementia, progressive muscular weakness, and paralysis.Bayle's disease paralytic dementia
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.