general paralysis of the insane

British  

noun

1.  GPI.  Also called: general paresis.   dementia paralytica.  a disease of the central nervous system: a late manifestation of syphilis, often occurring up to 15 years after the original infection, characterized by mental deterioration, speech defects, and progressive paralysis

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Example Sentences

The pair took pus from the sores of syphilitics and injected it into patients suffering from general paralysis of the insane.

From The New Yorker • May 20, 2019

Toward the end of the century, as many as one in five people entering asylums had general paralysis of the insane.

From The New Yorker • May 20, 2019

He had to be committed to the Northern State Hospital, where he died of "general paralysis of the insane."

From Time Magazine Archive

Noguchi and Moore have discovered the spirochæte in the brain in a number of cases of general paralysis of the insane.

From Manual of Surgery Volume First: General Surgery. Sixth Edition. by Thomson, Alexis

Most importance attaches to the fragility of the bones met with in general paralysis of the insane, locomotor ataxia, and other chronic diseases of the brain and spinal cord.

From Manual of Surgery Volume First: General Surgery. Sixth Edition. by Thomson, Alexis