globoid cell leukodystrophy

[ glōboid′ ]

n.

An inherited metabolic encephalopathy of infancy with rapidly progressive cerebral degeneration, massive loss of myelin, severe astrocytic gliosis, and infiltration of the white matter with characteristic multinucleate globoid cells.Krabbe's disease

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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.