glucocorticoid

American  

[gloo-koh-kawr-ti-koid] / ˌglu koʊˈkɔr tɪˌkɔɪd /

noun

Biochemistry.

1. any of a class of steroid hormones that are synthesized by the adrenal cortex of vertebrates and have anti-inflammatory activity.

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glucocorticoid British  

/ ˌɡluːkəʊˈkɔːtɪˌkɔɪd /

noun

1. any of a class of corticosteroids that control carbohydrate, protein, and fat metabolism and have anti-inflammatory activity

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Etymology

Origin of glucocorticoid

1945–50; gluco- + cortic(o)- ( def. ) + -oid; cf. corticosteroid

Example Sentences

The glucocorticoid cortisone is actually naturally present in the body as cortisol, a stress hormone.

From Science Daily • Apr. 10, 2024

"This study showed that the glucocorticoid receptor can only use regulatory regions that are already active in prostate cancer cells," says Doctoral Researcher Laura Helminen of the University of Eastern Finland.

From Science Daily • Apr. 10, 2024

In other words, glucocorticoid receptor-mediated drug resistance emerges through these regulatory regions, and by affecting the activity of these areas, the harmful effects of glucocorticoids in prostate cancer could be prevented.

From Science Daily • Apr. 10, 2024

Coregulator proteins were identified as an alternative target through which the glucocorticoid receptor affects the regulation of gene expression.

From Science Daily • Apr. 10, 2024

FOXA1 is known to have cancer-promoting properties, which is why the researchers assumed that inhibiting its activity would limit the development of glucocorticoid receptor-mediated drug-resistant prostate cancer.

From Science Daily • Apr. 10, 2024