glucocorticoid

American  

[gloo-koh-kawr-ti-koid] / ˌglu koʊˈkɔr tɪˌkɔɪd /

noun

Biochemistry.

1. any of a class of steroid hormones that are synthesized by the adrenal cortex of vertebrates and have anti-inflammatory activity.

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glucocorticoid British  

/ ˌɡluːkəʊˈkɔːtɪˌkɔɪd /

noun

1. any of a class of corticosteroids that control carbohydrate, protein, and fat metabolism and have anti-inflammatory activity

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Etymology

Origin of glucocorticoid

1945–50; gluco- + cortic(o)- ( def. ) + -oid; cf. corticosteroid

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Example Sentences

See Examples For:

glucocorticoid

This is because FOXA1 was found to be involved in the silencing of the glucocorticoid receptor gene, and this is what increased its activity when FOXA1 was inhibited.

From Science Daily ● Apr. 10, 2024

Surprisingly however, the effect was exactly the opposite: inhibiting the activity of FOXA1 further increased the activity of the glucocorticoid receptor -- and the development of drug resistance.

From Science Daily ● Apr. 10, 2024

The activity of the glucocorticoid receptor in regulatory regions can, however, be influenced in drug-resistant prostate cancer through an alternative pathway.

From Science Daily ● Apr. 10, 2024

However, recent studies have shown that the glucocorticoid receptor also has an oncogenic, or cancer-promoting, effect in cancers like breast and prostate cancer.

From Science Daily ● Apr. 10, 2024

Coregulator proteins were identified as an alternative target through which the glucocorticoid receptor affects the regulation of gene expression.

From Science Daily ● Apr. 10, 2024

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