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great foramen

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n.
The large orifice in the base of the skull through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata.foramen magnum
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The rainy weather could not ________ my elated spirits on my graduation day.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

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