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H-Y antigen

n.
  1. An antigen factor, dependent on the Y-chromosome, responsible for differentiating the human embryo into the male phenotype by inducing the embryonic gonad to develop into a testis.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.