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had unhinged

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But solutions can be found: in 2008, Greg Hicks transformed Stockmann into a Nordic Coriolanus at London's Arcola, and two years later Antony Sher at the Sheffield Crucible implied injustice had unhinged the hero's wits.

From The Guardian May 14, 2013

The shock had unhinged the poor man's reason: he lingered insane for eighteen months and died.

From In Clive's Command A Story of the Fight for India by Strang, Herbert

The resurrection of the past, the destruction of his happiness had unhinged his mind.

From The Man Who Rose Again by Hocking, Joseph

I started, now that this disclosure had unhinged my doubts; and subduing, as well as I was able, my rising emotion, I boldly asked who was "the happy man."

From Wilson's Tales of the Borders and of Scotland Volume 4 by Various

He believed that failure had unhinged his brother-in-law's mind; and knew for certain that no argument could possibly avail.

From A Practical Novelist by Davidson, John