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• mayo
  mayo

  noun

  mayonnaise.
• Mayo
  Mayo

  noun

  Charles Horace, 1865–1939, and his brother William James, 1861–1939, U.S. surgeons.

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Slang dictionary results for mayo.

mayo

¹ American  

[may-oh] / ˈmeɪ oʊ /

noun

Informal.

1. mayonnaise.

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Mayo ² American  

[may-oh] / ˈmeɪ oʊ /

noun

1. Charles Horace, 1865–1939, and his brother William James, 1861–1939, U.S. surgeons.

2. a county in NW Connaught province, in the NW Republic of Ireland. 2,084 sq. mi. (5,400 sq. km). Castlebar.

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Mayo ¹ British  

/ ˈmeɪəʊ /

noun

1. a county of NW Republic of Ireland, in NW Connacht province, on the Atlantic: has many offshore islands and several large lakes. County town: Castlebar. Pop: 117 446 (2002). Area: 5397 sq km (2084 sq miles)

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Mayo ² British  

/ ˈmeɪəʊ /

noun

1. a family of US medical practitioners. They pioneered group practice and established (1903) the Mayo Clinic in Rochester, Minnesota. Foremost among them were William Worrall Mayo (1819–1911), his sons William James Mayo (1861–1939) and Charles Horace Mayo (1865–1939), and Charles's son, Charles William Mayo (1898–1968)

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Usage

What else does mayo mean? Typically, mayo is short for mayonnaise, a classic condiment made of oil, vinegar, and egg yolks. When not, it can also be used as offensive language against white people or a slang term for drugs. Content warning: the following article deals with content related to illicit drugs and offensive and disparaging language.

Etymology

Origin of mayo

By shortening; cf. -o

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Example Sentences

See Examples For:

mayo Mayo

To assemble, spread sun-dried tomato pesto on one half of the bun and the lemon-garlic mayo on the other.

From Salon ● Nov. 5, 2026

Their crunch interrupts the softness of the turkey, cheese and sauces; their salt seasons the sandwich; and their pucker sharpens the lemon mayo and smoky-sweet romesco.

From Salon ● Jul. 30, 2026

Unlike bleach and wipes, a product made of buttermilk and mayo is not exactly designed for mass consumption.

From The Wall Street Journal ● Jul. 17, 2026

In the episode, Celenza uses the two for a breakfast sandwich, but mayo and hot sauce can be used in a multitude of meals: sandwiches, salads, marinades, hamburgers, tacos… do I need to keep going?

From Salon ● Jul. 2, 2026

Both Fred and I liked our sandwiches dry—no mustard, no mayo.

From "The Line Tender" by Kate Allen

He says he has donated more than $15 million to the Mayo Clinic, largely for aging research, and has backed longevity studies.

From The Wall Street Journal ● Nov. 12, 2026

“An annuity advertised as having no fees can still pay a commission to the adviser who sells it,” said James Mayo, a certified financial planner and principal of IronFjord Wealth Management.

From MarketWatch ● Nov. 6, 2026

Arteriosclerosis occurs when blood vessels carrying oxygen and nutrients from the heart to the body become thick and stiff, according to the Mayo Clinic.

From Los Angeles Times ● Oct. 30, 2026

It is believed the pair are originally from overseas but live in Ireland and were on a visit to Achill Island, off the County Mayo coast, when the incident happened.

From BBC ● Oct. 30, 2026

For Christmas, Carol gives me some Friendship’s Garden bath salts and Grace gives me a coloring book of Virginia Mayo.

From "Cat's Eye" by Margaret Atwood

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