- any antigen on the surface of tissue or blood cells that provokes the immune response and subsequent rejection when transplanted to an individual of a different antigenic type, thus determining whether the tissues or organs of a donor and recipient are histocompatible.
Origin of histocompatibility antigen
First recorded in 1965–70
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- a molecule occurring on the surface of tissue cells that can take several different forms. The differences between histocompatibility antigens are inherited and determine organ transplant rejection
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
- Any of various antigens on the surface of cell membranes that serve to identify a cell as self or nonself and are used to determine whether a tissue graft or transfusion will be accepted by a recipient.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.