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Huntington's disease

American  
[huhn-ting-tuhnz di-zeez] / ˈhʌn tɪŋ tənz dɪˌziz /

noun

Pathology.
  1. a hereditary disease of the central nervous system characterized by brain deterioration resulting in involuntary movement and unsteady gait, cognitive impairment and memory decline, and depression or other alterations in mood, with symptoms usually appearing in the fourth decade of life. HD


Huntington's disease British  
/ ˈhʌntɪŋtən /

noun

  1. Former name: Huntington's chorea.  a rare hereditary type of chorea, marked by involuntary jerky movements, impaired speech, and increasing dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of Huntington's disease

Named after George S. Huntington (1850–1916), U.S. physician, who described it in 1872

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In 2014, his team reported that CSE supported brain health in mice with Huntington's disease.

From Science Daily • Apr. 8, 2026

Prasad had reportedly been involved in the decision to request a new trial for uniQure’s experimental gene therapy for Huntington’s disease.

From MarketWatch • Mar. 9, 2026

The high-handed rejection of a treatment for Huntington’s disease shows why the biologics chief had to go.

From The Wall Street Journal • Mar. 8, 2026

Examples include Huntington's disease, myotonic dystrophy, and certain forms of ALS.

From Science Daily • Jan. 9, 2026

Within two years, HIV, cerebral palsy, Huntington's disease, blindness, polio, and male pattern baldness are eradicated.

From "We Are the Ants" by Shaun David Hutchinson

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