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hyaluronic acid

American  
[hahy-uh-loo-ron-ik, hahy-] / ˈhaɪ ə lʊˈrɒn ɪk, ˌhaɪ- /

noun

Biochemistry.
  1. a mucopolysaccharide serving as a viscous medium in the tissues of the body and as a lubricant in joints.


hyaluronic acid British  
/ ˌhaɪəlʊˈrɒnɪk /

noun

  1. a viscous polysaccharide with important lubricating properties, present, for example, in the synovial fluid in joints

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • hyaluronic adjective

Etymology

Origin of hyaluronic acid

1930–35; hyal(oid) (in reference to the vitreous humor, from which it was first isolated) + uronic acid ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Common ingredients include hyaluronic acid to help with hydration, peptides for skin plumping, retinals for fine lines and vitamin C for brightening the under-eye area.

From Los Angeles Times • Mar. 18, 2026

But as Robinson and Cohen emphasized, no athlete “has been accused of using shots of hyaluronic acid below the belt for the purposes of cheating at ski jumping.”

From The Wall Street Journal • Feb. 7, 2026

The filler used for liquid BBLs is often made up of hyaluronic acid, which is commonly used in facial filling treatments.

From BBC • Feb. 4, 2025

In 2010, a study published in the International Journal of Cosmetic Science found that the DNA in salmon sperm increased skin elasticity, collagen levels and production of hyaluronic acid compared to controls.

From Salon • Jul. 20, 2024

My cousin, who keeps urging me to add a hydrating serum with hyaluronic acid and vitamin C to my skincare regime.

From "Legendary Frybread Drive-In" by Cynthia Leitich Smith