- Biochemistry. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
- Pharmacology. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.
Origin of hyaluronidase
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
C20: hyalo- + Greek ouron urine + -id ³ + -ase
- Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.