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hydroxyzine

American  
[hahy-drok-suh-zeen] / haɪˈdrɒk səˌzin /

noun

Pharmacology.

  1. an antihistaminic compound, C 21 H 27 ClN 2 O 2 , used in the treatment of allergy, nausea, and anxiety.

Etymology

Origin of hydroxyzine

First recorded in 1955–60; hydroxy- + (pipera)zine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Hennawi zeroed in on three of her prescriptions: hydroxyzine, methocarbamol and gabapentin.

From The Wall Street Journal • Dec. 22, 2025

Those prescriptions—for everything from thiothixene for schizophrenia to hydroxyzine for anxiety—can be filled at one of 320 participating pharmacies around the state, at no cost to the inmate.

From Slate • Sep. 18, 2014

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.