hyperostosis corticalis deformans

[kôr′tĭ-kālĭs dē-fôrmănz′]
n.
  1. A hereditary disorder marked by irregular thickening of skull and bone cortex with thickening and widening of the shafts of long bones and elevated levels of serum alkaline phosphatase.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.