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hypoallergenic

American  
[hahy-poh-al-er-jen-ik] / ˌhaɪ poʊˌæl ərˈdʒɛn ɪk /
Or hypo-allergenic

adjective

  1. designed to reduce or minimize the possibility of an allergic response, as by containing relatively few or no potentially irritating substances.

    hypoallergenic cosmetics.


hypoallergenic British  
/ ˈhaɪpəʊˌæləˈdʒɛnɪk /

adjective

  1. (of cosmetics, earrings, etc) not likely to cause an allergic reaction

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of hypoallergenic

First recorded in 1950–55; hypo- + allergenic

Explanation

Anything hypoallergenic is unlikely to make you sneeze, wheeze, or break out in hives. In other words, it probably won't send your immune system into overdrive. When something is hypoallergenic, it's unlikely to cause an allergic reaction. Hypoallergenic cosmetics most likely won't make your skin break out in an itchy rash, and hypoallergenic dogs are your best bet if you want to convince your allergic dad to let you bring a puppy home. Keep in mind, though, that hypo- means "less," not "none" — it’s entirely possible that your adorable, hypoallergenic labradoodle will still make your dad sneeze.

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

For the fill, the best hotels opt for hypoallergenic down with medium firmness.

From The Wall Street Journal • Nov. 1, 2025

I was a suburban lacrosse mom and I was jeopardizing my 20-year marriage, two children, two hypoallergenic dogs, meticulously designed houses, swimming pools, gardeners and gutters.

From Los Angeles Times • Apr. 18, 2025

They are also hypoallergenic, which works well for any staffers with a cat allergy.

From BBC • Sep. 2, 2024

She used guayule latex to develop the first hypoallergenic medical glove to block both radiation and pathogens.

From Science Daily • Jan. 23, 2024

I become hyperactive and get a rash if I forget to use my hypoallergenic soap. if/whether.

From "Woe Is I" by Patricia T. O'Conner