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hypogonadism

American  
[hahy-puh-goh-na-diz-uhm, -gon-a-] / ˌhaɪ pəˈgoʊ næˌdɪz əm, -ˈgɒn æ- /
Also hypogonadia

noun

Pathology.
  1. diminished hormonal or reproductive functioning in the testes or the ovaries.

  2. a manifestation of this, as delayed pubescence or Klinefelter's syndrome.


Etymology

Origin of hypogonadism

First recorded in 1915–20; hypo- + gonad + -ism

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Previous research had revealed that mutations in genes associated with TACR3 led to a condition known as "congenital hypogonadism," resulting in reduced sex hormone production, including testosterone.

From Science Daily • Jan. 22, 2024

True hypogonadism involves low testosterone levels as well as symptoms and often has a clear cause, such as a genetic syndrome, chemotherapy, head trauma or a pituitary tumor, Dr. Anawalt said.

From New York Times • Jun. 16, 2023

Testosterone was isolated and synthesized in 1935 and first used to treat hypogonadism in men as well as tumor growth in women.

From Salon • Dec. 6, 2022

Unless someone has hypogonadism brought on by chemotherapy, infection or another serious medical condition, the FDA discourages its use.

From Seattle Times • Jun. 29, 2022

Reality check: Testosterone treatments are approved by the Food and Drug Administration only for men with diagnosed hypogonadism, a failure to produce enough testosterone because of disorders of the testicles, pituitary gland or brain.

From Washington Post • Jun. 1, 2015

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