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hypogonadism

American  
[hahy-puh-goh-na-diz-uhm, -gon-a-] / ˌhaɪ pəˈgoʊ næˌdɪz əm, -ˈgɒn æ- /
Also hypogonadia

noun

Pathology.
  1. diminished hormonal or reproductive functioning in the testes or the ovaries.

  2. a manifestation of this, as delayed pubescence or Klinefelter's syndrome.


Etymology

Origin of hypogonadism

First recorded in 1915–20; hypo- + gonad + -ism

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Clinical evidence has hinted at a close connection between low testosterone levels and anxiety, particularly in men with hypogonadism, a condition characterized by reduced sexual function.

From Science Daily • Jan. 22, 2024

Testosterone was isolated and synthesized in 1935 and first used to treat hypogonadism in men as well as tumor growth in women.

From Salon • Dec. 6, 2022

One brother died young of kidney failure after suffering from blindness, obesity, hypogonadism and mental deficiency; the other suffered longer after kidney dialysis machines became available.

From Washington Post • Jun. 28, 2022

There were just five TUEs other than for ADHD: two for hypogonadism and one each for altitude sickness, hypertension and sleep disorder.

From Seattle Times • Nov. 29, 2021

Although testosterone levels naturally decline with age, testosterone therapy is approved for use only in men with hypogonadism, an underlying endocrine disorder that typically results in a severe testosterone deficiency.

From New York Times • Jan. 29, 2014