IgE

American  

Immunology.

1. immunoglobulin E: a class of antibodies most abundant in tissue spaces, involved in the expulsion of intestinal parasites and causing allergic reactions by activating the release of histamines and leukotrienes in response to certain foreign antigens.

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Etymology

Origin of IgE

First recorded in 1960–65

Example Sentences

See Examples For:

IgE

"Mast cells pack a punch, when activated by IgE antibodies they can be said to explode and release inflammatory factors into the skin -- this is what causes itching and hives."

From Science Daily ● May 21, 2024

If the person already has IgE antibodies to the foods eaten before exercise, then the risk of triggering food allergy reactions is increased.

From Salon ● May 9, 2024

The troubling finding represents the first time that "IgE" antibodies to common foods have been linked to increased risk of cardiovascular mortality, the researchers report.

From Science Daily ● Nov. 9, 2023

IgE antibodies bind to a specific allergen — say, pollen or peanut — and trigger release of the chemical histamine, which makes people sneeze, itch, swell up, and, occasionally, go into anaphylaxis.

From Salon ● Aug. 15, 2023

Upon initial exposure to a potential allergen, an allergic individual synthesizes antibodies of the IgE class via the typical process of APCs presenting processed antigen to TH cells that stimulate B cells to produce IgE.

From Textbooks ● Jun. 9, 2022