IgE

American  

Immunology.

1. immunoglobulin E: a class of antibodies most abundant in tissue spaces, involved in the expulsion of intestinal parasites and causing allergic reactions by activating the release of histamines and leukotrienes in response to certain foreign antigens.

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Etymology

Origin of IgE

First recorded in 1960–65

Example Sentences

Food allergy symptoms that are not mediated by IgE are usually delayed reactions and called food intolerances or hypersensitivity.

From Salon • May 9, 2024

Medication doses were set based on each participant's body weight and IgE levels, with injections given once every two or four weeks, depending on the dose needed.

From Science Daily • Feb. 25, 2024

Approximately 15% of adults produce IgE antibodies in response to cow's milk, peanuts and other foods.

From Science Daily • Nov. 9, 2023

IgE antibodies bind to a specific allergen — say, pollen or peanut — and trigger release of the chemical histamine, which makes people sneeze, itch, swell up, and, occasionally, go into anaphylaxis.

From Salon • Aug. 15, 2023

IgA and IgD also have three constant domains per heavy chain, whereas IgM and IgE each have four constant domains per heavy chain.

From Textbooks • Jun. 9, 2022