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IgG

American  
Immunology.
  1. immunoglobulin G: a class of circulating antibodies predominant in serum, produced by plasma cells and memory cells in response to pathogens and other foreign substances, able to pass through the placental wall to the fetal circulation to impart immune defense for the period of infancy.


Etymology

Origin of IgG

First recorded in 1960–65

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Laboratory analyses showed strong IgG responses and neutralizing antibodies against SARS-CoV-2, along with immune-related proteins and metabolites linked to early host defense.

From Science Daily • Jan. 8, 2026

None of these differences, like IgG which is also in human breast milk, is necessarily harmful to humans.

From Salon • Jan. 19, 2024

To overcome this, the group led by professor Qiang Pan-Hammarström at Karolinska Institutet used genetic engineering to create IgA antibodies that bind to the SARS-CoV-2 spike protein in a similar way to the IgG antibodies.

From Science Daily • Jan. 10, 2024

There are five different classes of antibody found in humans: IgM, IgD, IgG, IgA, and IgE.

From Textbooks • Jun. 19, 2013

IgG is transferred from the maternal circulation to the fetus via the placenta, protecting the fetus from infection and protecting the newborn for the first few months of its life.

From Textbooks • Jun. 19, 2013