immune checkpoint therapy

[ih-myoon chek-point ther-uh-pee]

noun

Immunology, Pharmacology.

1. a form of cancer treatment that utilizes immune checkpoint inhibitors.

   It’s important to monitor T cell reactivation before and after immune checkpoint therapy.

Word History and Origins

Origin of immune checkpoint therapy¹

First recorded in 2015

Example Sentences

The treatments, often referred to as “immune checkpoint therapy”, have “fundamentally changed the outcome for certain groups of patients with advanced cancer”, it added.

Read more on Reuters

Immune checkpoint therapy has revolutionised cancer treatment, said the prize-giving Swedish Academy.

Read more on BBC

Sharma, P. & Allison, J. P. The future of immune checkpoint therapy.

Read more on Nature

A promising type of immunotherapy, called immune checkpoint therapy, blocks the “off” signal so your body has more time to mount its own defense.

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In December 2014, the PD-1 inhibitor nivolumab became the latest immune checkpoint therapy to gain FDA approval, specifically for the treatment of metastatic lung cancer3.

Read more on Nature