Dictionary.com
Thesaurus.com

immunosuppressive

American  
[im-yuh-noh-suh-pres-iv, ih-myoo-] / ˌɪm yə noʊ səˈprɛs ɪv, ɪˌmyu- /

adjective

  1. capable of causing immunosuppression.

    immunosuppressive drugs.


noun

  1. Pharmacology. Also immunosuppressor any substance that results in or effects immunosuppression.

immunosuppressive British  
/ ˌɪmjʊnəʊsəˈprɛsɪv /

noun

  1. any drug used for immunosuppression

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

adjective

  1. of or relating to such a drug

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • immunosuppressant noun

Etymology

Origin of immunosuppressive

First recorded in 1960–65; immuno- + suppressive ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The study uncovers a hidden mechanism by which cancer cells spread immunosuppressive PD-L1 through extracellular vesicles, allowing tumors to weaken immune responses far beyond their immediate environment.

From Science Daily • Jan. 28, 2026

Figures are different for immunosuppressive drug-only Part B coverage.

From The Wall Street Journal • Jan. 23, 2026

These include organ transplant patients who rely on immunosuppressive drugs, as well as individuals being treated long term for infections such as HIV or TB.

From Science Daily • Jan. 13, 2026

Organ transplant recipients are among the groups that could benefit most, since missing doses of immunosuppressive medication can quickly lead to organ rejection.

From Science Daily • Jan. 13, 2026

The lab's discovery was published in the paper, "Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma," in the journal Immunity.

From Science Daily • May 3, 2024