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involutional melancholia

noun Psychiatry.
  1. (formerly) extreme depression related to menopause or, less frequently, the male climacteric.
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Origin of involutional melancholia

First recorded in 1905–10
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

involutional melancholia in Medicine

involutional melancholia

n.
  1. A form of depression that occurs in late middle age, sometimes accompanied by paranoia.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.