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isoform

American  
[ahy-suh-fawrm] / ˈaɪ səˌfɔrm /

noun

isoforms plural
  1. Biochemistry. any of the variants of a particular protein, mostly similar to each other in function but having slightly different amino acid sequences.


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Example Sentences

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The researchers found thousands of isoform switches that occur during brain development, implicating previously uncharacterized RNA-binding proteins in cellular identity and cellular fate decisions.

From Science Daily • May 23, 2024

This gene encodes the protein ST2 in both receptor and decoy isoform, which binds to a cytokine called IL-33 that is involved in inflammatory and immunoregulation processes.

From Science Daily • May 21, 2024

It turns out that this one chaperone protein had a twin — it’s called an isoform.

From Washington Post • Sep. 24, 2021

The top and middle panels show isoform sequencing and RNA-seq reads, respectively, that have been mapped to the chromosomal location containing the AUR62017258 gene model, which is shown on the bottom panel.

From Nature • Feb. 7, 2017

The short deltaN isoform is thought to function as an oncogene, and its expression was most enriched in the classical subtype.

From Nature • Sep. 26, 2012

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