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isoform

American  
[ahy-suh-fawrm] / ˈaɪ səˌfɔrm /

noun

  • isoforms
    plural
  1. Biochemistry. any of the variants of a particular protein, mostly similar to each other in function but having slightly different amino acid sequences.


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Notably, an ancestry-biased mRNA isoform of SPSB2, likely driven by cross-population allele frequency differences in rs11064437, was found to be unannotated in canonical gene annotation.

From Science Daily Dec. 4, 2024

The researchers found thousands of isoform switches that occur during brain development, implicating previously uncharacterized RNA-binding proteins in cellular identity and cellular fate decisions.

From Science Daily May 23, 2024

It turns out that this one chaperone protein had a twin — it’s called an isoform.

From Washington Post Sep. 24, 2021

The top and middle panels show isoform sequencing and RNA-seq reads, respectively, that have been mapped to the chromosomal location containing the AUR62017258 gene model, which is shown on the bottom panel.

From Nature Feb. 7, 2017

The short deltaN isoform is thought to function as an oncogene, and its expression was most enriched in the classical subtype.

From Nature Sep. 26, 2012

This allowed the researchers to identify isoforms from hundreds of thousands of individual mouse and human brain cells.

From Science Daily Apr. 9, 2024

This protein comes in two different varieties termed "isoforms," which are known as gamma actin and beta actin.

From Science Daily Dec. 22, 2023

In their study, the researchers separated out the two isoforms and analyzed them individually.

From Science Daily Dec. 22, 2023

In nature, normally only mixtures of the two isoforms are found.

From Science Daily Dec. 22, 2023

Depending on the changes, the cells produce different forms, or isoforms, of proteins.

From Scientific American Jun. 8, 2023

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