Joffroy's sign

[ zhô-frwäz ]


An indication of exophthalmic goiter in which the facial muscles remain immobile when the eyeballs are rolled upward.
An indication of the early stages of brain disease in which an individual is unable to mentally compute simple mathematical calculations.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.