keratinocyte

American  

[ker-uh-tin-uh-sahyt, kuh-ra-tuhn-uh-sahyt] / ˌkɛr əˈtɪn əˌsaɪt, kəˈræ tən əˌsaɪt /

noun

plural

keratinocytes

1. a type of skin cell that synthesizes keratin and makes up most of the outer layer of the skin.

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Other Word Forms

• keratinocytic adjective

Example Sentences

This process could be linked to the initiation of programmed keratinocyte death, a natural process in the epidermis.

From Science Daily

Professor Amagai concludes: "Our study showed that epidermal hemoglobin was upregulated by oxidative stress and inhibited the production of reactive oxygen species in human keratinocyte cell cultures. Our findings suggest that hemoglobin ? protects keratinocytes from oxidative stress derived from external or internal sources such as UV irradiation and impaired mitochondrial function, respectively. Therefore, the expression of hemoglobin by keratinocytes represents an endogenous defense mechanism against skin aging and skin cancer."

From Science Daily

Studying mutations in these cells is difficult because the cells are rare compared with another type of epidermal cell, called a keratinocyte. b, The authors obtained biopsied samples of human skin, and isolated individual melanocyte cells from healthy individuals and from people with skin cancer.

From Nature

Barrandon, Y. & Green, H. Three clonal types of keratinocyte with different capacities for multiplication.

From Nature

Dynamic transcriptional and epigenetic regulation of human epidermal keratinocyte differentiation.

From Nature