kinetochore

American  

[ki-nee-tuh-kawr, -kohr, -net-uh-, kahy-] / kɪˈni təˌkɔr, -ˌkoʊr, -ˈnɛt ə-, kaɪ- /

noun

1. Biology. the place on either side of the centromere to which the spindle fibers are attached during cell division.

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Etymology

Origin of kinetochore

1930–35; kineto- + -chore < Greek chṓros place

Example Sentences

Next, we want to understand how the kinetochore -- the protein machinery that recognizes centromeres -- can accommodate such dramatic changes in centromere DNA over evolutionary time.

From Science Daily

Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells.

From Nature

To move and ultimately segregate each chromosome during division requires an attachment, or a physical interaction between the DNA and a specific group of proteins known as the kinetochore.

From Scientific American

Here, we used the Caenorhabditis elegans embryo as a model system to examine the crosstalk between two kinetochore protein complexes implicated in temporally distinct stages of attachment formation.

From Science Magazine

The molecular machinery that shepherds and literally pulls the chromosomes apart consists of paired microtubules radiating from opposite poles of the dividing cell and an enormous, but precise, molecular complex called a kinetochore.

From US News