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Laurence-Moon syndrome

n.
  1. An inherited syndrome attributed to recessive mutations of two genes on the same chromosome and characterized by mental retardation, pigmentary retinopathy, hypogenitalism, and spastic paraplegia.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.