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leptin

American  
[lep-tin] / ˈlɛp tɪn /

noun

  1. a hormone that is thought to suppress appetite and speed up metabolism.


leptin British  
/ ˈlɛptɪn /

noun

  1. a protein, produced by fat cells in the body, that acts on the brain to regulate the amount of additional fat laid down in the body

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

leptin Scientific  
/ lĕptĭn′ /
  1. A peptide hormone and neurotransmitter produced by fat cells and involved in the regulation of appetite.


Etymology

Origin of leptin

1995–2000; < Greek leptós small, thin + -in 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Blood tests also revealed meaningful improvements in markers linked to inflammation and immune function, including reduced levels of leptin and PAI-1.

From Science Daily Feb. 11, 2026

As to the science behind this, Dr Jenkinson points to the role of leptin, a hormone produced by fat cells.

From BBC Jan. 4, 2026

This means that, when we eat too quickly, we ingest more than we actually need – leptin does not have enough time to kick in and tell us that we have had enough.

From Salon Aug. 7, 2024

For the first factor, the researchers used mice genetically lacking a leptin receptor.

From Science Daily May 30, 2024

But that doesn’t work for people who have developed resistance to leptin, a hormone that suppresses appetite.

From Los Angeles Times Apr. 15, 2024

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