Lesch-Nyhan syndrome

[lĕshən]
n.
  1. A metabolic disorder that occurs in males, is associated with an enzyme deficiency, and is characterized by hyperuricemia and uric acid urolithiasis, choreoathetosis, mental retardation, spastic cerebral palsy, and self-mutilation of fingers and lips by biting.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.