[ lahy-geys, -geyz ]
/ ˈlaɪ geɪs, -geɪz /

noun Biochemistry.

any of a class of enzymes that catalyze the joining of two molecules by formation of a covalent bond accompanied by the hydrolysis of ATP.

Origin of ligase

1961; < Latin lig(āre) to tie, bind + -ase Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for ligase

/ (ˈlaɪˌɡeɪz) /


any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for ligase

[ līgās′, -gāz′ ]


Any of a class of enzymes, including the carboxylases, that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor.synthetase
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.