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light chain

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noun
Immunology. either of an identical pair of polypeptides in the antibody molecule that lie parallel to the upper parts of the heavy chain pair and are half the molecular weight.
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Also called L chain.

Origin of light chain

First recorded in 1960–65
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021

How to use light chain in a sentence

Medical definitions for light chain

light chain

n.
The smaller of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding portion with a variable amino acid sequence, and a constant region with an amino acid sequence that is relatively unchanging.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Scientific definitions for light chain

light chain

The smaller of the two types of polypeptide chains in an antibody molecule. A light chain consists of an antigen-binding portion with a variable amino acid sequence, and a constant region with an amino acid sequence that is relatively unchanging. The light chains are attached to the heavy chains so that the variable regions of both lie alongside each other. Compare heavy chain.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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