Dictionary.com
Thesaurus.com

long-acting

American  
[lawng-ak-ting, long-] / ˈlɔŋˈæk tɪŋ, ˈlɒŋ- /

adjective

Pharmacology.
  1. sustained-release.


long-acting British  

adjective

  1. (of a drug) slowly effective after initial dosage, but maintaining its effects over a long period of time, being slowly absorbed and persisting in the tissues before being excreted Compare intermediate-acting short-acting

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of long-acting

First recorded in 1950–55

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

If a patient’s body is already producing GLP-1 at normal or elevated levels, prescribing a long-acting agonist isn’t correcting a deficit; it may be amplifying a signal that’s already there.

From Slate • Mar. 22, 2026

Some of the women decided to take a long-acting contraceptive method, instead of the birth control pills, because they were worried about funding being cut again, she added.

From Salon • Feb. 9, 2026

One way for new entrants to compete with Lilly and Novo will be with long-acting alternatives to today’s weekly shots.

From Barron's • Jan. 12, 2026

Maternal vaccination during the third trimester of pregnancy and passive immunization of newborns using long-acting antibodies are being rolled out in many countries.

From Science Daily • Nov. 30, 2025

Metsera’s obesity portfolio, which includes a long-acting injection that would require fewer shots than Lilly’s drugs, clearly has potential to compete in that category.

From The Wall Street Journal • Nov. 2, 2025

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember "long-acting" for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com