loperamide

American  

[loh-per-uh-mahyd] / loʊˈpɛr əˌmaɪd /

noun

Pharmacology.

1. a substance, C 29 H 33 ClN 2 O 2 , used in the treatment of diarrhea.

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Etymology

Origin of loperamide

(ch)lo(rophenyl) + (pi)per(idine) + (butyr)amide, three of its chemical components

Example Sentences

The research team examined patients using a range of treatments, including Food and Drug Administration-approved IBS drugs, antidepressants, antispasmodics and opioid-based antidiarrheal medications such as loperamide and diphenoxylate, which are commonly recommended for symptom relief.

From Science Daily • Apr. 16, 2026

The primary ingredient in Imodium and similar drugs, loperamide, is intended to control diarrhea, with maximum-recommended doses ranging between 8 and 16 milligrams per day.

From Seattle Times • Jun. 7, 2016

Typically, loperamide acts on opioid receptors in the gastrointestinal tract and does not enter the central nervous system.

From New York Times • May 10, 2016

So Dr. Dasgupta used a test known as liquid chromatography-mass spectrometry to pinpoint loperamide as the culprit.

From New York Times • May 10, 2016

According to National Poison Center data, calls related to loperamide usage increased by 71 percent from 2011 to 2014.

From US News • May 5, 2016