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lose one's mind

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Also, lose one's reason. Go crazy, lose one's sanity, as in I thought she'd lost her mind when she said she was going ice-fishing, or That assignment is enough to make me lose my reason. The first expression dates from the late 1500s; the second employs reason in the sense of “unimpaired mental faculties,” a usage dating from the late 1300s. Also see under go out of one's mind; have all one's buttons.

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The American Heritage® Idioms Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.

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