Origin of lude
First recorded in 1975–80; by shortening
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019
slang shortening of quaalude, by 1973.
Online Etymology Dictionary, © 2010 Douglas Harper
A pill or tablet that contains the drug methaqualone.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.