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lupus

1 American  
[loo-puhs] / ˈlu pəs /
Lupus 2 American  
[loo-puhs] / ˈlu pəs /

noun

Astronomy.

genitive

Lupi
  1. the Wolf, a southern constellation between Centaurus and Norma.


lupus 1 British  
/ ˈluːpəs /

noun

  1. any of various ulcerative skin diseases

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Lupus 2 British  
/ ˈluːpəs /

noun

  1. a constellation in the S hemisphere lying between Centaurus and Ara

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

lupus Scientific  
/ lo̅o̅pəs /
lupus Cultural  
  1. An autoimmune disease that tends to strike women more frequently than men. The disease attacks the body's connective tissues.


Usage

In current usage the word lupus alone is generally understood to signify lupus vulgaris, lupus erythematosus being normally referred to in full or by the abbreviation LE

Other Word Forms

Etymology

Origin of lupus1

First recorded in 1580–90; from Medieval Latin, special use of Latin lupus “wolf”

Origin of Lupus2

From Latin

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In addition to MS, the virus has been linked to lupus, rheumatoid arthritis, and long COVID.

From Science Daily • Feb. 6, 2026

Once told by doctors that a lupus diagnosis could limit her ability to do so, Braxton stood onstage, still moving freely and hitting every note.

From Los Angeles Times • Feb. 2, 2026

Fatigue, brain fog, headaches, and joint pain can be caused by anemia, sleep disorders, mental illnesses, arthritis, multiple sclerosis, lupus, ALS, fibromyalgia, cancer, and many other conditions.

From Slate • Dec. 19, 2025

The argument over the restoration vs. eradication of canis lupus has raged here for years.

From The Wall Street Journal • Dec. 16, 2025

One could see that, for all the lupus and the purple eyes, she was uncommonly pretty.

From "Brave New World" by Aldous Huxley

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