verb (used with object), ly·oph·i·lized, ly·oph·i·liz·ing. Biochemistry.
  1. (of tissue, blood, serum, or the like) to dry by freezing in a high vacuum.
Also especially British, ly·oph·i·lise.

Origin of lyophilize

First recorded in 1935–40; lyophil(ic) + -ize
Related formsly·oph·i·li·za·tion, noun Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for lyophilization



  1. (tr) to dry (blood, serum, tissue, etc) by freezing in a high vacuum; freeze dry
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

lyophilization in Medicine


  1. The process of isolating a solid substance from solution by freezing the solution and vaporizing the ice away under vacuum conditions.freeze-drying
Related formsly•ophi•lize′ (-līz′) v.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.