macromutation

[ mak-roh-myoo-tey-shuhn ]
/ ˌmæk roʊ myuˈteɪ ʃən /

noun Genetics.

a mutation that has a profound effect on the resulting organism, as a change in a regulatory gene that controls the expression of many structural genes.

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Origin of macromutation

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021