noun Chemistry.

a very large molecule, as a colloidal particle, protein, or especially a polymer, composed of hundreds or thousands of atoms.

Origin of macromolecule

First recorded in 1885–90; macro- + molecule
Related formsmac·ro·mo·lec·u·lar [mak-roh-muh-lek-yuh-ler] /ˌmæk roʊ məˈlɛk yə lər/, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for macromolecule



any very large molecule, such as a protein or synthetic polymer
Derived Formsmacromolecular (ˌmækrəʊməˈlɛkjʊlə), adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for macromolecule

1886, from macro- + molecule. Apparently coined in "On Macro-molecules, with the Determinations of the Form of Some of Them," by Anglo-Irish physicist G. Johnstone Stoney (1826–1911). Originally of crystals. Meaning "molecule composed of many atoms" is from 1935, from German makromolekul (1922). Related: Macromolecular.

Online Etymology Dictionary, © 2010 Douglas Harper

macromolecule in Medicine




A very large molecule, such as a protein, consisting of many smaller structural units linked together.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

macromolecule in Science



A large molecule, such as a protein, consisting of many smaller molecules linked together.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.