macular degeneration

American  

noun

Ophthalmology.

1. degeneration of the central portion of the retina, resulting in a loss of sharp vision.

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macular degeneration British  

noun

1. pathological changes in the macula lutea, resulting in loss of central vision: a common cause of blindness in the elderly

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macular degeneration Scientific  

/ măk′yə-lər /

1. A progressive condition, usually seen in the elderly, characterized by a gradual loss of vision in the central area of the visual field and eventual blindness.

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Example Sentences

Apellis has two approved drugs: Empaveli, which is approved to treat two rare kidney diseases, and Syforvre, which is used by patients with geographic atrophy, an advanced form of dry age-related macular degeneration.

From MarketWatch • Mar. 31, 2026

Vivien Hillgrove, writer, producer and first-time director on this film, was enjoying a 50-year career of movie editing when she started losing her sight to a form of macular degeneration.

From The Wall Street Journal • Jan. 22, 2026

"Stem cell-derived retinal implants may offer one of the greatest possibilities for helping patients with dry age-related macular degeneration and one day, may offer a cure."

From Science Daily • Jan. 9, 2026

She has macular degeneration and is considered legally blind, though she has been able to function at home.

From MarketWatch • Dec. 30, 2025

What I didn't mention is that as a result of macular degeneration in both eyes, she is now blind.

From Underground by Dreyfus, Suelette