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macular degeneration

American  

noun

Ophthalmology.
  1. degeneration of the central portion of the retina, resulting in a loss of sharp vision.


macular degeneration British  

noun

  1. pathological changes in the macula lutea, resulting in loss of central vision: a common cause of blindness in the elderly

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

macular degeneration Scientific  
/ măkyə-lər /
  1. A progressive condition, usually seen in the elderly, characterized by a gradual loss of vision in the central area of the visual field and eventual blindness.


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Apellis has two approved drugs: Empaveli, which is approved to treat two rare kidney diseases, and Syforvre, which is used by patients with geographic atrophy, an advanced form of dry age-related macular degeneration.

From MarketWatch Mar. 31, 2026

Vivien Hillgrove, writer, producer and first-time director on this film, was enjoying a 50-year career of movie editing when she started losing her sight to a form of macular degeneration.

From The Wall Street Journal Jan. 22, 2026

This figure includes people with wet macular degeneration, which is less common but typically more severe.

From Science Daily Jan. 9, 2026

Roughly 20 million Americans are living with age-related macular degeneration.

From Science Daily Jan. 9, 2026

What I didn't mention is that as a result of macular degeneration in both eyes, she is now blind.

From Underground by Dreyfus, Suelette

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